Connect with us

How Resection Surgery Can Boost Lung Transplant Success

General

How Resection Surgery Can Boost Lung Transplant Success

Lung cancer is one of the most common and deadly types of cancer in the world. According to the World Health Organization, it caused 1.8 million deaths in 2020, accounting for 18% of all cancer deaths. For some patients with advanced lung cancer, a lung transplant may be the only option to extend their lives. However, lung transplant is a complex and risky procedure, with many potential complications and challenges. One of the most important factors that affect lung transplant survival rates is the condition of the donor lung. In this article, we will explore how resection surgery, a type of lung cancer surgery, can improve the quality and function of the donor lung, and thus increase the chances of a successful lung transplant.

What is Resection Surgery?

Resection surgery is a surgical procedure that removes part of the lung that is affected by the tumor. Depending on the size and location of the tumor, there are different types of resection surgery:

  1. Lobectomy: This is the most common type of resection surgery, which removes one lobe of the lung. The lung has five lobes, three on the right and two on the left. Each lobe is a separate section of the lung that has its own blood supply and airways. A lobectomy can remove up to 20% of the lung’s capacity.
  2. Segmentectomy: This is a less invasive type of resection surgery, which removes a segment of the lung. A segment is a smaller subdivision of a lobe, and there are about 10 segments in each lung. A segmentectomy can remove up to 10% of the lung’s capacity.
  3. Wedge resection: This is the least invasive type of resection surgery, which removes a wedge-shaped piece of the lung. A wedge resection can remove up to 5% of the lung’s capacity.

The goal of resection surgery is to remove the tumor and some of the surrounding healthy tissue, while preserving as much of the lung function as possible. Resection surgery can be done as a standalone treatment for early-stage lung cancer, or as a part of a multimodal treatment that includes chemotherapy and/or radiation therapy for more advanced stages.

How Resection Surgery Can Improve Lung Transplant Survival Rates

Lung transplant is a life-saving procedure that replaces a diseased lung with a healthy one from a donor. However, lung transplant is not a cure for lung cancer, and it comes with many challenges and risks. One of the major causes of death after lung transplant is primary graft dysfunction (PGD), which occurs when the transplanted lung is damaged by inflammation, fluid leakage, and poor oxygen exchange. PGD can occur within the first 72 hours after the transplant, and it can lead to acute respiratory failure, infection, organ rejection, and death.

One of the factors that can influence the development and severity of PGD is the quality of the donor lung. A donor lung that has a tumor, infection, or other damage can increase the risk of PGD and reduce the survival rates of the recipient. Therefore, it is crucial to select a suitable donor lung that is free of any abnormalities and has a good match with the recipient’s blood type, tissue type, and size.

Resection surgery can improve the quality and function of the donor lung by removing the tumor and preserving as much healthy lung tissue as possible. This can reduce the risk of PGD and improve the oxygenation and ventilation of the transplanted lung. Resection surgery can also improve the quality of life and the long-term outcomes for lung transplant recipients, as they can have better lung function, lower risk of infection and rejection, and lower need for immunosuppressive drugs .

Conclusion

Resection surgery is a type of lung cancer surgery that removes part of the lung affected by the tumor. It can be done as a lobectomy, a segmentectomy, or a wedge resection, depending on the size and location of the tumor. Resection surgery can improve lung transplant survival rates by reducing the risk of primary graft dysfunction, a major cause of death after lung transplant. Primary graft dysfunction occurs when the transplanted lung is damaged by inflammation, fluid leakage, and poor oxygen exchange. Resection surgery can prevent or minimize these problems by removing the tumor and preserving as much healthy lung tissue as possible. This can improve the quality of life and the long-term outcomes for lung transplant recipients.

Continue Reading
You may also like...

More in General

Popular Post

To Top